St. Louis Foot and Ankle Surgeon

Update: Dr. Wolfe is excited to announce he is now with Mercy Orthopedics!

Biography: Dr. Jesse Wolfe completed his Bachelor of Science in Biology from Bethel University in St. Paul, Minnesota while competing in collegiate athletics with the Bethel University Royals football program in 2012. He furthered his education at Des Moines University College of Podiatric Medicine and Surgery in Des Moines, Iowa, where he received his doctorate degree. Dr. Wolfe continued his training in St. Louis, where he completed his residency training with SSM Health DePaul Hospital Foot and Ankle Surgery Program and a traveling orthopedic fellowship with the German Society of Foot and Ankle Surgery in 2019. Dr. Wolfe joins Mercy Orthopedics following his experience as a member of a surgically active orthopedic practice in Iowa for the past three years.

During his medical, residency training, and active practice, Dr. Wolfe has published numerous articles and book chapters on advanced foot and ankle surgical techniques and has continued to remain active in advancing the field of foot and ankle surgery. He has served as an editor for the Journal of Foot and Ankle Surgery Scientific Literature Reviews and on the board of the Heartland Foot and Ankle Scientific Conference Committee as well as the Missouri Podiatric Medial Association Scientific Committee and is an active Board Member for the State of Missouri. His training and leadership in the field were recently recognized with the honorable distinction of Top Doctor and Top Professional by Marquis Who’s Who publication in 2022. Dr. Wolfe has also been featured in the Wall Street Journal and was selected as the cover feature with Millenium Magazine for 2023. In addition, Dr. Wolfe enjoys his teaching roles as adjunct faculty for Des Moines University College of Osteopathic Medicine and with the University of Texas San Antonio.

Dr. Wolfe is board certified with the American Board of Foot and Ankle Surgery and an active fellow of the American College of Foot and Ankle Surgery. His interests include Arthroscopy, Sports Medicine, Minimally Invasive Surgery, Trauma, Total Ankle Replacement, and Advanced Foot and Ankle Reconstruction. Dr. Wolfe sees patients at the Mercy Orthopedic Clinic in Troy, MO and at the Mercy Clinic Zumbehl location. Dr. Wolfe has privileges at Mercy Hospital St. Louis, Mercy South, and Mercy Hospital Lincoln.

Areas of Practice


Arthroscopy

Arthroscopy is an advanced surgical procedure used to treat orthopaedic conditions which offers less risk and remarkable results for patients.

This procedure is also known as arthroscopic surgery.  Surgeons perform this minimally invasive surgical procedure to correct orthopaedic joint trauma/conditions by inserting an arthroscope into a small incision in the compromised area.


Ankle Instability

Your ankle is a hinge joint that allows motion up and down, and from side to side. Your foot and ankle have several ligaments. These are strong band-like structures that keep the bones in your ankle tightly connected. On the outer side of your foot, you have several ligaments. These include the anterior talofibular ligament (ATFL) and the calcaneofibular ligament (CFL). These help keep your ankle and foot steady when you walk.

If you have had repeated ankle sprains or if you have certain foot deformities, your ligaments can start to get weak and loose. If this happens, your ankle may become unstable.

During lateral ankle ligament reconstruction, the surgeon makes a small incision on the outside of your ankle. This is done while you are under general anesthesia. Then your surgeon tightens one or more of the ligaments on the outside of your foot.


Total Ankle Replacement

Total Joint Replacement is a surgical procedure in which parts of an arthritic or damaged joint are removed and replaced with a metal or plastic prosthesis.

In a total joint replacement (also called arthroplasty), the damaged bone and cartilage is removed and replaced with prosthetic components.  Dr. Wolfe specializes in total ankle replacement.

If nonsurgical treatments like medications and using walking supports are no longer helpful, you may want to consider total ankle replacement surgery. Joint replacement surgery is a safe and effective procedure to relieve pain, correct leg deformity, and help you resume normal activities. 


“Dr. Wolfe is amazing, he literally gave me my life back. I am soo grateful for his expertise on tendon surgery.”

– Melissa P.

Get in Touch

Schedule an appointment today! Call us at 636-528-3407